News: Growth Hormone Receptor

Zeranol, a chemical used in the U.S. to stimulate cattle growth, is known to increase the growth of hormone receptor positive human breast cancer cells. This new study finds that this effect is increased in the presence of leptin, a fat hormone. The authors conclude that overweight women may be more susceptible to beef's pro-breast cancer effects.

Ghrelin may influence the development of obesity through its role in the control of energy balance, food intake, and regulation of body weight. The effects of ghrelin are mediated via the growth hormone secretagogue receptor (GHSR).

Dysregulation of normal apoptotic mechanisms provides a growth advantage to cancer cells [1]. In breast cancer, dysregulated apoptotic pathways include down-regulated death receptor pathway function,mutations, and abnormal bcl-2 pathway function [2-4] Furthermore, breast cancer treatments including chemotherapy, radiation therapy and hormonet

Special receptors on the surfaces of these cells trigger cancerous cell division in response to a particular growth hormone,When diagnosed with malignant gliomas, the sufferer typically has just 14 months to live. There is currently no effective treatment for the fast-spreading illness